Table 1.

−1 PRF inhibition IC₅₀ values. IC₅₀ values found from fitting dose–response of −1 PRF inhibition for SARS-CoV-2 frameshift signal (Figure S3).

Inhibitor	IC50 (μM)
nafamostat	0.5 ± 0.4
abemaciclib	0.6 ± 0.2
palbociclib	0.6 ± 0.3
valnemulin	0.04 ± 0.03