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. 2022 Feb 10;23(4):1963. doi: 10.3390/ijms23041963

Figure 1.

Figure 1

HS biosynthesis. (A) Extension of HS from proteoglycan. (B) Enzyme reaction of modification in HS. Note that SULF1 and SULF2 are involved in the removal of 6-O-sulfate in the last 2 steps. (C) Chemical structure of ΔUA-GlcNAc.