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Effects of PL48 inhibitor on (A) HepG2 and (B) MCF7 cell proliferation. Cells growing in the log phase were incubated with MEM (HepG2) or RPMI-1640 (MCF7) in the presence or absence of PL48 at concentrations of up to 10 μM for 24 or 48 h. Cell number was determined by crystal violet staining and expressed as a percentage of the control cells. These experiments were performed twice in triplicate. * p < 0.05, *** p < 0.0001.
