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Effects of PL48 treatment on choline uptake (A) and on total cellular activity of ChoK (B) in HepG2 and MCF7 cancer cell lines. Cells were incubated with the inhibitor for 48 h, and after its withdrawal, choline uptake and ChoKα activity were determined. Data represent the mean ± SEM of two independent experiments conducted in triplicate. Results are normalised to their respective controls. * p < 0.05, *** p < 0.0001.
