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. 2022 Feb 16;14(2):426. doi: 10.3390/pharmaceutics14020426

Table 1.

Effect of PL48 on [methyl-14C]choline incorporation in HepG2 and MCF7. Cells were treated with 1 μM PL48 for 48 h. Then, they were incubated with [methyl-14C]choline as described in the methods section. The total incorporation of choline and the incorporation of choline into ChoP and PC are expressed as nmol of choline incorporated per mg of cell protein and represent the mean ± SEM of two independent experiments conducted in triplicate. * p < 0.05.

HepG2 MCF7
Total ChoP PC Total ChoP PC
Control 32.11 ± 2.09 23.74 ± 1.56 7.15 ± 0.61 13.46 ± 0.99 9.64 ± 0.62 2.21 ± 0.62
1 μM PL48 20.89 ± 1.33 * 16.3 ± 1.49 * 3.37 ± 0.30 * 10.22 ± 0.41 * 6.70 ± 0.63 * 2.38 ± 0.23