Table 4.
Associations between serum Trx80 and CSF AD biomarkers in the GEDOC cohort
| Total | SCI | MCI | 6AD | |||||
|---|---|---|---|---|---|---|---|---|
| N | β (p) | N | β (p) | N | β (p) | N | β (p) | |
| Aβ42 | 99 | − 0.14 (0.23) | 37 | 0.21 (0.38) | 31 | − 0.15 (0.50) | 31 | − 0.12 (0.56) |
| t-tau | 99 | 0.12 (0.31) | 37 | − 0.36 (0.08)# | 31 | − 0.23 (0.29) | 31 | 0.29 (0.17) |
| p-tau | 99 | 0.13 (0.27) | 37 | − 0.48 (0.02) | 31 | − 0.03 (0.89) | 31 | 0.27 (0.20) |
| p-tau/t-tau | 99 | − 0.07 (0.55) | 37 | − 0.07 (0.73) | 31 | 0.41 (0.05) | 31 | − 0.21 (0.34) |
Values are standardized β coefficients (p values) from linear regression models with serum Trx80 levels as a dependent variable. Linear regressions are adjusted for age. p values considered significant (bold) if p < 0.05; #, p < 0.10. N, number of participants with available data for each analysis