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. 2022 Feb 24;14:37. doi: 10.1186/s13195-022-00979-9

Table 7.

Serum Trx80 associations with ApoE4 and MMSE scores from the combined dataset

FINGER SCI MCI AD
N β (p) N β (p) N β (p) N β (p)
ApoE4 carriers (yes/no) 14/32 0.30 (0.05) 6/9 0.41 (0.50) 10/12 0.59 (0.02) 6/8 − 0.28 (0.55)
MMSE 47 0.21 (0.17) 25 − 0.05 (0.81) 23 − 0.41 (0.05) 25 − 0.03 (0.87)

Values are standardized β coefficients (p values) from linear regression models with serum Trx80 levels as a dependent variable in FINGER and GEDOC cohorts. Linear regression models are adjusted for age. In ApoE4 regression models, a positive coefficient is interpreted as Trx80 being higher in ApoE4 carriers. p values considered significant (bold) if p < 0.05. N, number of participants with available data for each analysis