Table 7.
FINGER | SCI | MCI | AD | |||||
---|---|---|---|---|---|---|---|---|
N | β (p) | N | β (p) | N | β (p) | N | β (p) | |
ApoE4 carriers (yes/no) | 14/32 | 0.30 (0.05) | 6/9 | 0.41 (0.50) | 10/12 | 0.59 (0.02) | 6/8 | − 0.28 (0.55) |
MMSE | 47 | 0.21 (0.17) | 25 | − 0.05 (0.81) | 23 | − 0.41 (0.05) | 25 | − 0.03 (0.87) |
Values are standardized β coefficients (p values) from linear regression models with serum Trx80 levels as a dependent variable in FINGER and GEDOC cohorts. Linear regression models are adjusted for age. In ApoE4 regression models, a positive coefficient is interpreted as Trx80 being higher in ApoE4 carriers. p values considered significant (bold) if p < 0.05. N, number of participants with available data for each analysis