Table 1.

The selected flavonoids and the binding strength score against MEK1 (Autodock Vina docking energy, X-Score binding energy and $p{K}_d$). The higher the absolute values of the scores, the better the binding.

Rank	Flavonoids	Docking Affinity (kcal/mol)	Binding Energy (Kcal/mol)	$\mathit{p}{\mathit{K}}_{\mathit{d}}$ $\mathbf{or}-\mathbf{log}\left({\mathit{K}}_{\mathit{d}}\right)$
1	129696793	−10.8	−10.25	7.52
2	10813589	−10.6	−10.96	8.03
3	10991656	−10.5	−9.49	6.95
4	10524567	−10.5	−10.83	7.94
5	10575055	−10.4	−10.11	7.41
Native		−9.0	−8.95	6.56