Table 2.
Candidates of molecular targeting drugs for vascular anomalies.
Diseases | Target | Drug |
---|---|---|
VEGF receptor | Pazopanib | |
PROS | PI3K | Alpelisib |
PROS | Akt | Miransertib |
Venous malformation Lymphatic malformation |
mTOR | Rapamycin |
Arteriovenous malformation | BRAF | Vemurafenib |
Arteriovenous malformation | MEK | Trametinib |