Figure 3. Systemic and airway physiology measurement after exosome delivery.

WT C57BL/6 mice were treated with LPS exosomes for 1 week (n = 5 per group). Airway physiology was determined using flexiVent for measures of airway resistance (A) and FEV0.1 (B). (C) The systemic impact of exosome delivery were measured by Fulton’s index. Statistical analyses were performed using Wilcoxon’s signed-rank test; *P < 0.05, **P < 0.01. Data are shown as median and IQR (representative of n = 2 independent experiments).