Table A3.
Average score (0–4) for hemorrhage for untreated wounds, wounds treated with wild type L. reuteri R2LC or ILP100 in Cohort A and wounds treated with placebo or ILP100 wounds in Cohort B. For time points not included in the table, all wounds in all groups were scored as 0. * p < 0.05.
| Hemorrhage (Mean ± SEM) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cohort A | Day 2 | Day 3 | Day 5 | Day 7 | Day 9 | Day 11 | Day 13 | n;N |
| Untreated | 0.50 (± 0.62) | 0.22 (± 0.10) | 0.33 (± 0.11) | 0.28 (± 0.14) | 0.89 (± 0.08) | 0.11 (± 0.08) | 0.03 (± 0.03) | 3;18 |
| Wild type R2LC | 0.75 (± 0.22) | 0.08 (± 0.08) | 0.33 (± 0.14) | 1.42 (± 0.15) * | 0.83 (± 0.17) | 0.00 (± 0.00) | 0.00 (± 0.00) | 3;12 |
| ILP100 | 0.17 (± 0.07) | 0.10 (± 0.06) | 0.23 (± 0.08) | 1.17 (± 0.11) * | 0.30 (± 0.09) * | 0.00 (± 0.00) | 0.00 (± 0.00) | 6;30 |
| Cohort B | - | Day 3 | - | Day 7 | Day 9 | Day 11 | Day 13 | n;N |
| Placebo | - | 1.17 (± 0.12) | - | 0.39 (± 0.12) | 0.56 (± 0.12) | 0.61 (± 0.12) | 0.11 (± 0.08) | 3;18 |
| ILP100 | - | 0.47 (± 0.13) * | - | 0.94 (± 0.09) * | 0.47 (± 0.08) | 0.22 (± 0.07) * | 0.06 (± 0.04) | 6;36 |