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. 2022 Feb 21;12(2):323. doi: 10.3390/jpm12020323

Table 2.

The number of patients with BRCA or HRD status in the included studies.

Author Study Year No. of Patients No. of Patients with pCR
mBRCA+ WtBRCA HRD+ HRD- mBRCA+ WtBRCA HRD+ HRD-
Fasching et al. [22] GeparPLA 2020 20 16 27 12 6 16
Mayer et al. [23] TBCRC030 2020 6 69 39 17 1 5 5 1
Yuan et al. [24] NCT01525966 2020 11 44 8 20
Sharma et al. [25] NeoSTOP 2020 17 65 13 32
Fontaine et al. [26] BSMO 2019 9 42 7 22
Hahnen et al. [28], Loibl.S et al. [27] GeparSixto 2017,
2018
26 120 74 27 17 66 48 11
Loibl et al. [29], Telli et al. [30] BrighTNess 2018 70 406 225 104 38 222 138 42
Sella et al. [35] 2018 14 23 9 10
Sharma et al. [31] PROGECT 2017 27 133 16 75
Connolly et al. [32] TBCRC 008 2016 12 6 8 1
Telli et al. [33] PrECOG 0105 2015 17 73 50 15 9 22 33 3
Kaklamani et al. [34] NCT01372579 2015 3 27 12 14 2 11 9 2
Silver et al. [36] 2010 2 26 2 4

Abbreviations: HRD: homologous recombination deficiency; pCR: pathological complete response CR: complete response; mBRCA: mutated BRCA; WtBRCA: wildtype BRCA.