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. Author manuscript; available in PMC: 2022 Feb 25.
Published in final edited form as: Lab Chip. 2019 Jul 31;19(17):2769–2785. doi: 10.1039/c9lc00389d

Figure 5. Schematic of DMA chip and DMP chip for nucleic acid extraction.

Figure 5

(A) DMA chip for RNA isolation. a:Cell lysis. Different components including DNA, RNA and protein are released. b:on-chip RNA isolation. RNA is bound and eluted by controlling pH. Adapted from Ref. 79 with permission from the Elsevier. (B) DMP chip for DNA and RNA isolation. (a) Chemical structure of DMP and schematic drawing for assembling of a plastic type microfluidic cartridge with a 3D disposable chip. (b) schematic and photograph workflows for the DMP system for RNA (b) and DNA (c) extraction. Adapted from Ref. 20 with permission from ACS Publications.