Table 2. Univariable and Multivariable Cox Proportional Hazard Regression Analysis of Factors Affecting Relapse-Free Survival in Patients with pIMA (n = 41).
| Variables | Univariable Analysis | Multivariable Analysis | |||
|---|---|---|---|---|---|
| Unadjusted HR (95% CI) | P | Adjusted HR (95% CI) | P | ||
| Age, years | 0.98 (0.94–1.02) | 0.337 | |||
| Sex | |||||
| Male | Reference | ||||
| Female | 1.19 (0.51–2.78) | 0.697 | |||
| Smoking status | |||||
| Non-smoker | Reference | ||||
| Ex- or current-smoker | 1.17 (0.50–2.74) | 0.716 | |||
| Lesion characteristics | |||||
| Fraction of involved segments in a lobe (unit = 0.1) | 1.32 (1.13–1.53) | < 0.001 | 1.32 (1.13–1.53) | < 0.001 | |
| Cavity | 3.51 (1.52–8.13) | 0.003 | 3.51 (1.52–8.13) | 0.003 | |
| Separate nodule(s) | 4.66 (1.95–11.11) | < 0.001 | 4.66 (1.95–11.11) | < 0.001 | |
| SUVmax (unit = 1) | 1.23 (1.06–1.43) | 0.006 | |||
| Adjuvant treatment | |||||
| None | Reference | ||||
| Adjuvant chemotherapy | 1.75 (0.77–3.97) | 0.180 | |||
CI = confidence interval, HR = hazard ratio, pIMA = pneumonic-type invasive mucinous adenocarcinoma, SUVmax = maximum standardized uptake value