Table 3. Univariable and Multivariable Cox Proportional Hazard Regression Analysis of Factors Affecting Overall Survival in Patients with pIMA (n = 41).
| Variables | Univariable Analysis | Multivariable Analysis | |||
|---|---|---|---|---|---|
| Unadjusted HR (95% CI) | P | Adjusted HR (95% CI) | P | ||
| Age, years | 1.04 (0.99–1.09) | 0.114 | |||
| Sex | |||||
| Male | Reference | ||||
| Female | 0.98 (0.33–2.87) | 0.968 | |||
| Smoking status | |||||
| Non-smoker | Reference | ||||
| Ex- or current-smoker | 1.15 (0.39–3.38) | 0.794 | |||
| Smoking amount (pack-years) | 1.00 (0.97–1.03) | 0.917 | |||
| Lesion characteristics | |||||
| Fraction of involved segments in a lobe (unit = 0.1) | 1.19 (0.98–1.44) | 0.082 | |||
| Cavity | 1.95 (0.69–5.48) | 0.206 | |||
| Separate nodule(s) | 4.53 (1.59–12.89) | 0.005 | 4.53 (1.59–12.89) | 0.005 | |
| SUVmax (unit = 1) | 1.32 (1.13–1.53) | < 0.001 | |||
| Adjuvant treatment | |||||
| None | Reference | ||||
| Adjuvant chemotherapy | 1.11 (0.40–3.08) | 0.995 | |||
CI = confidence interval, HR = hazard ratio, pIMA = pneumonic-type invasive mucinous adenocarcinoma, SUVmax = maximum standardized uptake value