Table 1.

Comparison of hydrodynamic size and zeta potential data between NP-Chi-xPEI-DNA and recently reported biodegradable PEI-based DNA carriers in literature.

Non-Viral DNA Carrier Material	Hydrodynamic Size	Zeta Potential	Reference
NP-Chi-xPEI-DNA	45.8 nm	18.3 mV	N/A
2,6-pyridinedicarboxaldehyde-Crosslinked 1.8k PEI	160–250 nm	17–27 mV	[29]
Disulfide-crosslinked 2k PEI modified with tyrosine	135.6 nm	62.1 mV	[31]
Disulfide-crosslinked 2.5k PEI	350–500 nm	20–40 mV	[32]
Disulfide and bisepoxide crosslinked 6k PEI	200 nm	20 mV	[34]
Oxidized glutathione crosslinked 0.6k PEI	200–400 nm	30 mV	[52]
Disulfide-crosslinked 1.8k PEI modified with cyclodextrin and poly-glutamic acid	250 nm	20 mV	[53]
Diglycidyl-1,2-cyclohexanedicarboxylate-crosslinked 10k PEI	125–201 nm	11–20 mV	[54]