Figure 2.

Concentration-effect curves of α-PVP, 3-F-α-PVP, 4-F-α-PVP, 3-Cl-α-PVP, 4-Cl-α-PVP, 3,4-Cl₂-α-PVP, 3-Br-α-PVP, 4-Br-α-PVP, and cocaine on [³H]MPP+ uptake and [³H]WIN35,428 binding at DAT (Panel (A,C)) and [³H]5-HT uptake and [³H]Imipramine binding at SERT (Panel (B,D)) in transfected HEK293 cells. Data are expressed as a percentage of control uptake (mean ± SEM) of six independent experiments performed per triplicate.