Table 1.

Mutations of VOCs compared with wild type in RBD [11] and corresponding affinity to ACE2 [9,10].

Strain	First Reported Country	Mutations in RBD	Affinity to ACE2
Wild type	Wuhan	K417, L452, T478, E484, N501	20.5 × 10−9 M
Alpha (B.1.1.7)	United Kingdom	N501Y	6.2 × 10−9 M
Beta (B.1.351)	South Africa	K417N, E484K, N501Y	10.3 × 10−9 M
Gamma (P.1)	Brazil	K417T, E484K, N501Y	/
Kappa (B.1.617.1)	India	L452R, E484Q	4.6 × 10−9 M