Table 4. Disease-free survival based on the antioxidant gene signature and clinical data for sarcoma.
| Univariate Cox analysis | Multivariate Cox analysis | ||||||
| HR | 95%CI | P | HR | 95%CI | P | ||
| Age | 1.010 | 0.998–1.023 | 0.112 | ||||
| Sex (Female) | 1.086 | 0.765–1.543 | 0.644 | ||||
| Ethnicity (Asian) | |||||||
| Black | 2.125 | 0.265–17.053 | 0.478 | ||||
| White | 1.915 | 0.266–13.795 | 0.519 | ||||
| Histological type (DLP) | |||||||
| LMS | 0.799 | 0.514–1.243 | 0.320 | ||||
| MFS | 0.735 | 0.378–1.429 | 0.364 | ||||
| Other | 0.702 | 0.345–1.430 | 0.330 | ||||
| UPS | 0.775 | 0.439–1.368 | 0.380 | ||||
| Tumor site (Extremity) | 0.977 | 0.675–1.414 | 0.902 | ||||
| Metastasis (No) | 4.915 | 3.126–7.728 | 0.000 | 3.942 | 3.942–6.524 | 0.000 | |
| Margin status (R0) | 2.085 | 1.422–3.056 | 0.000 | 1.971 | 1.971–3.306 | 0.010 | |
| Multifocal indicator (No) | 2.075 | 1.309–3.289 | 0.002 | 1.493 | 1.493–3.077 | 0.277 | |
| Radiotherapy (No) | 1.175 | 0.788–1.752 | 0.430 | ||||
| Pharmacotherapy (No) | 1.385 | 0.865–2.219 | 0.175 | ||||
| Risk score | 1.005 | 1.003–1.007 | 0.000 | 1.016 | 1.007–1.025 | 0.000 | |
HR, hazard ratio; CI, confidence interval; DLP, dedifferentiated liposarcoma; LMS, leiomyosarcoma; MFS, myxofibrosarcoma; UPS, undifferentiated pleomorphic sarcoma.