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. 2022 Feb 10;14(3):1407–1428. doi: 10.18632/aging.203885

Table 4. Disease-free survival based on the antioxidant gene signature and clinical data for sarcoma.

Univariate Cox analysis Multivariate Cox analysis
HR 95%CI P HR 95%CI P
Age 1.010 0.998–1.023 0.112
Sex (Female) 1.086 0.765–1.543 0.644
Ethnicity (Asian)
Black 2.125 0.265–17.053 0.478
White 1.915 0.266–13.795 0.519
Histological type (DLP)
LMS 0.799 0.514–1.243 0.320
MFS 0.735 0.378–1.429 0.364
Other 0.702 0.345–1.430 0.330
UPS 0.775 0.439–1.368 0.380
Tumor site (Extremity) 0.977 0.675–1.414 0.902
Metastasis (No) 4.915 3.126–7.728 0.000 3.942 3.942–6.524 0.000
Margin status (R0) 2.085 1.422–3.056 0.000 1.971 1.971–3.306 0.010
Multifocal indicator (No) 2.075 1.309–3.289 0.002 1.493 1.493–3.077 0.277
Radiotherapy (No) 1.175 0.788–1.752 0.430
Pharmacotherapy (No) 1.385 0.865–2.219 0.175
Risk score 1.005 1.003–1.007 0.000 1.016 1.007–1.025 0.000

HR, hazard ratio; CI, confidence interval; DLP, dedifferentiated liposarcoma; LMS, leiomyosarcoma; MFS, myxofibrosarcoma; UPS, undifferentiated pleomorphic sarcoma.