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. 2022 Feb 14;14(3):1492–1507. doi: 10.18632/aging.203889

Table 2. Clinical characteristics of the BLCA patients.

Overall High risk Low risk p
N 403 201 202
Age (mean (SD)) 68.06 (10.60) 69.54 (10.05) 66.58 (10.94) 0.005
Gender = Female/Male (%) 105/298 (26.1/73.9) 60/141 (29.9/70.1) 45/157 (22.3/77.7) 0.106
Grade (%) <0.001
 High Grade 380 (94.3) 197 (98.0) 183 (90.6)
 Low Grade 20 (5.0) 1 (0.5) 19 (9.4)
 Unknown 3 (0.7) 3 (1.5) 0 (0.0)
Stage (%) <0.001
 Stage I 1 (0.2) 0 (0.0) 1 (0.5)
 Stage II 127 (31.5) 44 (21.9) 83 (41.1)
 Stage III 138 (34.2) 74 (36.8) 64 (31.7)
 Stage IV 133 (33.0) 82 (40.8) 51 (25.2)
 Unknown 4 (1.0) 1 (0.5) 3 (1.5)
T (%) 0.001
 T0 1 (0.2) 0 (0.0) 1 (0.5)
 T1 3 (0.7) 1 (0.5) 2 (1.0)
 T2 37 (9.2) 8 (4.0) 29 (14.4)
 T2a 25 (6.2) 9 (4.5) 16 (7.9)
 T2b 56 (13.9) 27 (13.4) 29 (14.4)
 T3 42 (10.4) 23 (11.4) 19 (9.4)
 T3a 69 (17.1) 32 (15.9) 37 (18.3)
 T3b 80 (19.9) 49 (24.4) 31 (15.3)
 T4 10 (2.5) 9 (4.5) 1 (0.5)
 T4a 43 (10.7) 27 (13.4) 16 (7.9)
 T4b 5 (1.2) 4 (2.0) 1 (0.5)
 TX 1 (0.2) 0 (0.0) 1 (0.5)
 Unknown 31 (7.7) 12 (6.0) 19 (9.4)
M (%) 0.015
 M0 193 (47.9) 82 (40.8) 111 (55.0)
 M1 11 (2.7) 8 (4.0) 3 (1.5)
 MX 197 (48.9) 110 (54.7) 87 (43.1)
 Unknown 2 (0.5) 1 (0.5) 1 (0.5)
N (%) 0.028
 N0 234 (58.1) 104 (51.7) 130 (64.4)
 N1 46 (11.4) 31 (15.4) 15 (7.4)
 N2 75 (18.6) 43 (21.4) 32 (15.8)
 N3 7 (1.7) 5 (2.5) 2 (1.0)
 NX 36 (8.9) 15 (7.5) 21 (10.4)
 Unknown 5 (1.2) 3 (1.5) 2 (1.0)
RiskScore (median [IQR]) 1.18 [0.72, 1.76] 1.76 [1.50, 2.14] 0.72 [0.43, 0.95] <0.001