Figure 7.

Predicted binding mode and predicted intermolecular interactions of most abundant compounds in O. pillopillo leaves extract and the residues of Torpedo Californica acetylcholinesterase (TcAChE) catalytic site. Yellow dotted lines indicates hydrogen bond interactions, cyan dotted lines represents π-π interactions, magenta dotted lines represents T-shaped interactions, blue dotted lines represents π -cation interactions and red dotted lines represents salt bridges. (A). 5-hydroxy-7-methoxy-2-phenyl-4H-chromen-4-one into the catalytic site; (B). Luteolin 7,4′-dimethyl ether into the catalytic site; (C). Apigenin 5-glucoside into the catalytic site; (D). Quercetin 3-O-ß -D-2″-acetylglucuronide into the catalytic site; (E). Quercetin 3-O-ß-D-2″-acetylglucuronide methyl ester into the catalytic site; (F). Quercetin 3-O-(ß-D-glucuronide) into the catalytic site; (G). Quercetin 3-O-ß -D-(glucuronide methyl ester) into the catalytic site; (H). 8-O-metyl daphnin, (daphnetin 7 O-glucose, 8-methyl ether) into the catalytic site.