Table 1.
Patients’ demographic and clinicopathological characteristics.
| Variables | Adjuvant Chemotherapy (n = 161) |
No Adjuvant Chemotherapy (n = 372) |
p-Value | ||
|---|---|---|---|---|---|
| n | (%) | n | (%) | ||
| Sex | |||||
| Male | 80 | (49.7) | 167 | (44.9) | 0.308 |
| Female | 81 | (50.3) | 205 | (55.1) | |
| Age (years) | |||||
| Mean ± SD | 64.3 ± 9.9 | 70.5 ± 11.2 | <0.001 * | ||
| Median | 65.9 | 726 | |||
| BMI (kg/m2) | |||||
| Mean ± SD | 24.5 ± 4.0 | 23.9 ± 3.8 | 0.386 | ||
| Median | 24.1 | 23.8 | |||
| Follow-up (months) | |||||
| Mean ± SE | 60.1 ± 7.6 | 51.2 ± 7.8 | <0.001 * | ||
| Median | 46.8 | 29.0 | |||
| ASA | |||||
| 1 | 2 | (2.0) | 4 | (2.4) | 0.009 * |
| 2 | 51 | (50.0) | 50 | (29.8) | |
| 3 | 49 | (48.0) | 113 | (67.3) | |
| 4 | 0 | (0.0) | 1 | (0.6) | |
| ECOG | |||||
| 0 | 58 | (46.8) | 98 | (41.0) | 0.293 |
| 1 | 55 | (44.4) | 102 | (42.7) | |
| 2 | 10 | (8.1) | 31 | (13.0) | |
| 3 | 1 | (0.8) | 4 | (1.7) | |
| 4 | 0 | (0.0) | 4 | (1.7) | |
| Smoking | |||||
| No | 85 | (72.0) | 182 | (71.7) | 0.940 |
| Yes | 33 | (28.0) | 72 | (28.3) | |
| Tumor location | |||||
| Renal pelvis | 80 | (49.7) | 202 | (54.3) | 0.317 |
| Ureter | 50 | (31.1) | 92 | (24.7) | |
| Renal pelvis + ureter | 31 | (19.3) | 78 | (21.0) | |
| Tumor size | |||||
| <1 cm | 3 | (2.3) | 10 | (3.2) | 0.760 |
| ≥1 and <2 cm | 22 | (16.5) | 39 | (12.7) | |
| ≥2 and <3 cm | 26 | (19.5) | 56 | (18.2) | |
| ≥3 cm | 82 | (61.7) | 203 | (65.9) | |
| Histological variant | |||||
| No | 135 | (83.9) | 322 | (86.6) | 0.412 |
| Yes | 26 | (16.1) | 50 | (13.4) | |
| Tumor grade | |||||
| Low grade | 12 | (7.5) | 15 | (4.1) | 0.098 |
| High grade | 148 | (92.5) | 355 | (95.9) | |
| Multifocality | |||||
| No | 102 | (63.4) | 234 | (62.9) | 0.921 |
| Yes | 59 | (36.6) | 138 | (37.1) | |
| Concurrent CIS | |||||
| No | 141 | (87.6) | 325 | (87.4) | 0.946 |
| Yes | 20 | (12.4) | 47 | (12.6) | |
| Lymphovascular invasion | |||||
| No | 99 | (61.5) | 245 | (65.9) | 0.333 |
| Yes | 62 | (38.5) | 127 | (34.1) | |
| Pathological stage | |||||
| Stage III | 128 | (79.5) | 308 | (83.2) | 0.301 |
| Stage IV | 33 | (83.2) | 62 | (16.7) | |
| Pathological T stage | |||||
| pT3 | 146 | (90.7) | 326 | (87.6) | 0.310 |
| pT4 | 15 | (9.3) | 46 | (12.4) | |
| Pathological N stage | |||||
| pN0 | 38 | (23.6) | 74 | (19.9) | 0.011 * |
| pN1 | 10 | (6.2) | 10 | (2.7) | |
| pN2 | 12 | (7.5) | 10 | (2.7) | |
| pNx | 98 | (60.9) | 272 | (73.1) | |
* p < 0.05.