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. 2022 Jan 18;8(2):92. doi: 10.3390/jof8020092

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effects of proteasome inhibitors on tunicamycin tolerance. (A) Cultures of the indicated strains, BY4741 wild-type (wt) slt2, ire1, and hac1 were assayed for growth on MPD-SDS (0.003%) plates lacking (control) or containing tunicamycin (Tn) at the indicated concentration (μg/mL) and/or 75 μM MG132. (B) The same strains that in (A) were tested for growth in the presence of tunicamycin (Tn) at the indicated concentration (μg/mL) and/or 50 μM of bortezomib or delanzomib. A representative experiment is shown.