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. 2022 Feb 14;11(4):514. doi: 10.3390/plants11040514

Table 2.

Kinetic parameters of acetylcholinesterase inhibition by extracts of R. officinalis.

Inhibitor Concentration
(µM; µg/mL)
Km (µM) V max
Galanthamine 0 2.14 ± 0.13 0.38 ± 0.09
2 5.47 ± 0.17 0.29 ± 0.06
5 9.76 ± 0.25 0.21 ± 0.07
10 17.38 ± 0.33 0.15 ± 0.05
Ethyl-acetate 50 4.21 ± 0.28 0.32 ± 0.08
100 7.19 ± 0.41 0.28 ± 0.10
150 8.28 ± 0.63 0.23 ± 0.08
Ethanol 50 3.05 ± 0.21 0.35 ± 0.05
100 4.65 ± 0.12 0.30 ± 0.06
150 6.24 ± 0.53 0.28 ± 0.08
Aqueous 50 2.50 ± 0.09 0.34 ± 0.09
100 3.67 ± 0.11 0.31 ± 0.04
150 4.22 ± 0.29 0.27 ± 0.07