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. 2022 Feb 9;10(2):399. doi: 10.3390/microorganisms10020399

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The secondary metabolic gene clusters evolution. (I) Whole genome phylogeny of B. halotolerans strains highlighting the endophytic bacterial strains Cal.l.30, Cal.f.4 and Cal.l.11. The numbers above branches are pseudo-bootstrap support values from 100 replications. Inferred clusters are for B. halotolerans strains harboring (Cluster B) or lacking (Cluster A) the iturin/ mojavensin A BGC. (II) Number and distribution heatmap of the secondary metabolite biosynthetic gene clusters (iturin/ mojavensin A, fengycin/ plipastatin, surfactin, bacillaene, bacilysin, bacillibactin, subtilosin A and FAS-PKS) detected (green) or not (red) among B. halotolerans strains. B. halotolerans strains Cal.l.30, Cal.l.11 and Cal.f.4 are highlighted in red.