Table 2.

SVD radiological features.

Subtypes of SVD Neuroradiological Aspect
Recent small subcortical infarct	• Recent infarction in one perforating arteriole and its territory • Increased DWI, FLAIR, T2-weighted signal • Decreased T1-weighted signal • Iso-intense T2-weighted GRE signal
WMHs	• Increase intensity or hyperintensity on T2-weighted, T2 weighted GRE and FLAIR signal • Iso-intense on DWI and T1-weighted signal • Decrease intensity or hypointense on T1-weighted signal
Lacune	• Round or ovoid fluid filed cavity mostly in subcortical region • Hyperintensity on T2-weighted signal • Decreased signal in FLAIR and T1-weighted images • Signal similar to CSF • Decreased or iso-intense signal on DWI
Perivascular space	• Fluid-filled spaces that follow the typical course of a vessel as it goes through gray or white matter similar signal intensity with CSF • Decrease FLAIR and T1-weighted signal • IncreasedT2-weighted-signal • DW1 and T2- weighted GRE signal seems iso-intense
Cerebral microbleed	• Small, rounded areas of signal void • Iso-intense DWI, FLAIR, 12- and-weighted signal • Best seen in T21 weighted GRE with decreased signal

SVD: small vessel disease; WMHs: white matter hyperintensities; DWI: diffusion weighted imaging; FLAIR: fluid attenuated inversion recovery; GRE: gradient echo; CSF: cerebrospinal fluid.