Table 2.
Characterization of blank and drug-loaded micelles.
| Sample | mPEG-hyd-aPHB | mPEG-b-aPHB | ||||||
|---|---|---|---|---|---|---|---|---|
| Size [nm] | PDI | DLC [%] |
DLE [%] |
Size [nm] | PDI | DLC [%] |
DLE [%] |
|
| Blank micelles | 55.3 ± 2.8 | 0.14 ± 0.01 | _ | _ | 49.5 ± 4.1 | 0.18 ± 0.02 | _ | _ |
| DOX-loaded micelles | 85.7 ± 5.1 | 0.22 ± 0.03 | 5.3 ± 0.4 | 48.6 ± 3.1 | 82.8 ± 6.2 | 0.2 ± 0.01 | 5.7 ± 0.2 | 54.1 ± 3.8 |
| 8HQ-loaded micelles | 77.7 ± 3.8 | 0.19 ± 0.02 | 6.0 ± 0.1 | 55.1 ± 1.9 | 87.9 ± 2.9 | 0.15 ± 0.02 | 5.8 ± 0.4 | 55.3 ± 2.3 |
| 8HQ-Glu-loaded micelles | 104.9 ± 4.5 | 0.25 ± 0.03 | 5.2 ± 0.2 | 45.6 ± 2.2 | 100.8 ± 3.1 | 0.28 ± 0.04 | 5.1 ± 0.3 | 47.1 ± 2.6 |
| 8HQ-Gal-loaded micelles | 92.5 ± 4.2 | 0.22 ± 0.02 | 5.3 ± 0.3 | 46.4 ± 2.5 | 99.9 ± 5.4 | 0.19 ± 0.02 | 5.3 ± 0.3 | 48.1 ± 3.2 |