Table 4.
Selectivity index (SI) of tested compounds after 72 h incubation time.
| Compound | Selectivity Index (SI) a | |
|---|---|---|
| MCF-7 | HCT-116 | |
| DOX | 4.75 | 25.81 |
| DOX-micelles | 19.23 | 32.05 |
| 8HQ | 3.20 | 2.19 |
| 8HQ-mic b | 5.29 | 4.36 |
| 8HQ-Glu | 0.47 | 1.39 |
| 8HQ-Glu-mic c | 22.68 | 35.21 |
| 8HQ-Gal | 0.74 | 0.81 |
| 8HQ-Gal-mic d | 14.68 | 164.12 |
a Selectivity index (SI) was calculated as a ratio of the IC50 value for healthy cells (NHDF-Neo) and the IC50 value for cancer cells (MCF-7 or HCT-116); b 8HQ-loaded micelles; c 8HQ-Glu-loaded micelles; d 8HQ-Gal-loaded micelles.