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. 2022 Jan 28;15(2):162. doi: 10.3390/ph15020162

Figure 3.

Figure 3

(A): UV-HPLC chromatograms (288 nm) of reference iodinated compounds (S)-14, (S)-18 and (S)-21; (B): Radioactivity-HPLC chromatograms of the corresponding radiotracers (S)-[125I]14 ([125I]5-iodo-L-TIC(OH)), (S)-[125I]18 ([125I]6-iodo-L-TIC(OH)) and (S)-[125I]21 ([125I]8-iodo-L-TIC(OH)) obtained after semi-preparative RP-HPLC purification and formulation. The radioactivity detector was connected in series after the UV detector accounting for a slight difference in retention times (≈0.3 min) observed between 125I and 127I products.