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Diagnostic algorithm in pediatric-onset CMP. The algorithm brings light to a step-by-step method for the clinical approach when facing the management of a cohort with CMP in children. Abbreviations: CF, clinical features; CMP, cardiomyopathy; CPK; creatine phosphokinase; ECG electrocardiography; FGF21, fibroblast growth factor 21; GAG, glycosaminoglycan; MRI, magnetic resonance imaging; GDF15, growth differentiation factor 15; NGS, next-generation sequencing; US, ultrasound.
