TABLE 1.

Summary of meningioma‐related genes covered by the NGS meningioma panel

Gene	Region	Frequency (%) current study	Frequency (%) literature	References
NF2	cds	43	43	[6]
AKT1	E17K	15	5–13.6 [30]	[6, 7] ([11])
TRAF7	cds	13	20–28.9	[7, 19]
PIK3CA	cds	10	6	[8]
KLF4	K409Q	6	8.8	[7]
SMO	L412F, W535L	6	5 [28]	[6] ([10])
SUFU	cds	6	Somatic rare	[7]
PIK3R1	cds	3	0.6	[7]
SMARCE1	cds	1	rare	[20]
SMARCB1	cds	1	6	[6, 8]
TERT	C228T, C250T	1	6.4	[21]
POLR2A	hotspots	0	6	[8]
CDKN2A/B	cds	0	5	[18]
BAP1	cds	0	Somatic rare	[22]

Abbreviation: cds, coding DNA sequence and splice sites.