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. 2021 Nov 14;32(2):e13035. doi: 10.1111/bpa.13035

FIGURE 2.

FIGURE 2

pTau‐S396 levels are not altered in ALS motor cortex white matter. (A) Top. Representative thionin immunostaining in white matter from (a) AD EC, (b, c) control mCTX, and (d, e) ALS mCTX. Bottom. Representative pTau‐S396 immunostaining in white matter from (f) AD EC, (g, h) control mCTX, and (i, j) ALS mCTX. (B) There was no significant change in pTau‐S396 levels in ALS mCTX WM (n = 16) compared with controls (n = 7) (Mann–Whitney U test = 34.50, p = 0.1574). Bulbar onset C9ORF72‐ALS is indicated with a red dot, limb onset C9ORF72‐ALS with a blue dot, and a single ALS case revealing brain alterations likely due to AD is indicated with a green dot. Scale bar: 50 µm