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. 2021 Nov 14;32(2):e13035. doi: 10.1111/bpa.13035

FIGURE 3.

FIGURE 3

PHF1 levels are not altered in ALS post‐mortem motor cortex. (A) Top. Representative thionin immunostaining in grey matter from (a) AD EC, (b, c) control mCTX, and (d, e) ALS mCTX. Bottom. Representative PHF1 immunostaining in grey matter from (f) AD EC, (g, h) control mCTX, and (i, j) ALS mCTX. (B) There was no significant change in PHF1 levels in ALS mCTX (n = 12) compared with controls (n = 7) (Mann–Whitney U test = 34.50, p = 0.5483). Bulbar onset C9ORF72‐ALS is indicated with a red dot, limb onset C9ORF72‐ALS with a blue dot, and a single ALS case revealing brain alterations likely due to AD is indicated with a green dot. Scale bar: 50 µm