Table 1.
Properties of selected 99mTc-labeled MPI agents.
| [99mTc]Tc-Sestamibi | [99mTc]Tc-Tetrofosmin | [99mTc]Tc-Teboroxime | [99mTc]Tc-3SPboroxime | |
|---|---|---|---|---|
| Chemical characteristics | cationic | cationic | neutral | neutral |
| Kit formulation | available | available | available | available |
| Myocardial uptake at rest (%) | 1 | 1.2 | 3–4 * | 4–5 |
| Heart/to liver ratio 15–20 min post-injection at rest | 0.5 | 0.8 | negligible | 0.8 |
| First pass extraction (%) | 65 | 54 | 88 | - |
| Redistribution | negligible | none | significant | - |
| Excretion | hepatobiliary | renal and hepatobiliary | hepatobiliary and renal |
* soon after injection.