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. Author manuscript; available in PMC: 2022 Jun 14.
Published in final edited form as: ACS Biomater Sci Eng. 2021 Mar 10;7(6):2430–2443. doi: 10.1021/acsbiomaterials.0c01803

Figure 3.

Figure 3.

MCF-7 sensitivity to ER inhibitors. (A–G) Proliferation analysis of the MCF-7 cells treated with 1 nM of E2 and 10 nM Tamoxifen and 10 nM of Fulvestrant cultured on (A) TCP, (B) gelatin, (C) collagen I gel, (D) RCF, (E) ACF, (F) R-PCL, and (G) A-PCL substrates. (H) Proliferation analysis of MCF-7 cells treated with 1 nM of E2 and 100 nM of Tamoxifen on TCP, RCF, and ACF; data are relative to TCP without estrogen and with Tam100 nM. Data represent the average of three to four independent experiments with n = 3–4, SE, *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001, presented as the fold change relative to the TCP substrate without estrogen (vehicle) shown in graph A.