Table 1.
Characteristics of SARS-CoV-2 Variants of Interest (VOI).
| Linage | Named | First Identified | WHO Label | Spike Protein Substitutions |
|---|---|---|---|---|
| B.1.427 | 452R | United States (California) | Epsilon (ε) | L452R, D614G |
| B.1.429 | 452R | United States (California) | Epsilon (ε) | S13I, W152C, L452R, D614G |
| B.1.525 | 484K | United Kingdom/Nigeria | Eta (η) | A67V, 69del, 70del, 144del, E484K, D614G, Q677H, F888L |
| B.1.526 | 484K | United States (New York) | Iota (ι) | L5F, (D80G*), T95I, (Y144-*), (F157S*), D253G, (L452R*), (S477N*), E484K, D614G, A701V, (T859N*), (D950H*), (Q957R*) |
| B.1.617.1 | 154K | India | Kappa (κ) | (T95I), G142D, E154K, L452R, E484Q, D614G, P681R, Q1071H |
| B.1.617.3 | 20A | India | Not named | T19R, G142D, L452R, E484Q, D614G, P681R, D950N |
| P.2 | 20J | Brazil (Rio de Janeiro) | Zeta (ζ) | E484K, (F565L*), D614G, V1176F |
(*) = detected in some sequences but not all. Adapted from CDC: SARS-CoV-2 Variant Classifications and Definitions (https://www.cdc.gov/coronavirus/2019-ncov/variants/variant-info.html#Interest, accessed on 15 September 2021).