Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Feb 10;14(2):392. doi: 10.3390/pharmaceutics14020392

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Cell viability of chicken fibroblasts (CEC-32 cell line) exposed to toltrazuril-loaded nanocapsules based on membrane damage (LIVE/DEAD^® Viability/Cytotoxicity Kit) after (A) 24, (B) 48 and (C) 72 h. Data represent mean ± SD (n = 3−4). * p < 0.05 vs. C(−) (one-way ANOVA, post hoc Dunnett’s test). NC_S100 = blank Eudragit^® S100 nanocapsules; NC_S100t = toltrazuril-loaded Eudragit^® S100 nanocapsules; LNC = blank lipid core nanocapsules; LNCt = toltrazuril-loaded lipid core nanocapsules; C(+) = positive control; C(−) = negative control. Blank formulations (NC_S100 and LNC) were added the same volume, respectively, to the drug-loaded nanoformulation.

Cell viability of chicken fibroblasts (CEC-32 cell line) exposed to toltrazuril-loaded nanocapsules based on membrane damage (LIVE/DEAD^® Viability/Cytotoxicity Kit) after (A) 24, (B) 48 and (C) 72 h. Data represent mean ± SD (n = 3−4). * p < 0.05 vs. C(−) (one-way ANOVA, post hoc Dunnett’s test). NC_S100 = blank Eudragit^® S100 nanocapsules; NC_S100t = toltrazuril-loaded Eudragit^® S100 nanocapsules; LNC = blank lipid core nanocapsules; LNCt = toltrazuril-loaded lipid core nanocapsules; C(+) = positive control; C(−) = negative control. Blank formulations (NC_S100 and LNC) were added the same volume, respectively, to the drug-loaded nanoformulation.