Table 3.

IC₅₀ of several parts of A. muricata against cancer cell lines.

Plant Parts	Cancer Cell Line	IC50	Refs.
Leaf, twig, and root	HL-60 human leukemia cell line	6–49 µg/mL	[10]
Leaf	A-549 lung cancer cell line	5.09 µg/mL	[18]
Leaf	MCF7 breast cancer cell line	Ethanolic extract: 5.3 µg/mL; ethyl acetate fraction: 2.86 µg/mL; n-hexane fraction: 3.08 µg/mL; water fraction: 48.31 µg/mL	[23]
Leaf	PC-3 human prostate cancer cell line	63 µg/mL	[21]
Annomuricin E from leaves	HT-29 colon cancer cell line	1.62 µg/mL	[22]
Annoniacin from seeds	ECC-1 and HEC-1 human endometrial cancer cell lines	4.62–4.75 µg/mL	[24]