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. 2022 Feb 18;10(2):332. doi: 10.3390/vaccines10020332

Figure 1.

Figure 1

Humoral and cellular immune responses in SARS-CoV-2-recovered individuals. (a) SARS-CoV-2 S1 IgG ELISA ratio; (b) pVNT50 titer; (c) IFN-γ ELISpot counts from visit one to visit four for unvaccinated and vaccinated individuals. The arrow indicates the vaccination time in the single-dose-vaccinated group. (d) SARS-CoV-2 S1 IgG ELISA ratio; (e) pVNT50 titer; (f) IFN-γ ELISpot counts from visit one to visit four in unvaccinated individuals from the longitudinal study. (g) SARS-CoV-2 S1 IgG ELISA ratio; (h) pVNT50 titer; (i) IFN-γ ELISpot counts from visit one to visit four in single-dose-vaccinated individuals from the longitudinal study. The blue dashed line indicates the cutoff (S1-IgG = 0.8 for negative and 1.1 for positive, pVNT50 = 10). The significance of the differences between the unvaccinated and single-dose-vaccinated groups was determined using two-way ANOVA by Holm–Šídák’s multiple comparisons test. ns, p > 0.05, **** p < 0.0001.