AAAD |
Aromatic amino acid decarboxylase |
AD |
Alzheimer’s disease |
AKT1 |
RAC-alpha serine/threonine-protein kinase |
ALS |
Amyotrophic lateral sclerosis |
AMBRA1 |
Autophagy and beclin-1 regulator 1 |
AMP |
Adenosine monophosphate |
AMPK |
AMP protein kinase |
AP1/2 |
Adaptor protein ½ |
APP |
Amyloid precursor protein |
Arp2/3 |
Actin-related proteins 2/3 |
ATG9 |
Autophagy-related protein 9 |
ATG13 |
Autophagy-related protein 13 |
ATG101 |
Autophagy-related protein 101 |
BARA |
β-α Repeated autophagy |
BCL-2 |
Apoptosis regulator B-cell lymphoma 2 Bcl-2 |
BCL-XL |
B-cell lymphoma-extra large |
CALB1 |
Calbindin-D28K |
Cav1.2 |
Voltage-dependent L-type calcium channel subunit α-1C |
Cav1.3 |
Calcium channel, voltage-dependent, L-type, α-1D subunit |
CCD |
Coiled-coil domain |
CI-MPR |
Cation-independent-mannose-6-phosphate receptor |
CMA |
Chaperone-mediated autophagy |
COX-1 |
Cyclooxygenase-1 |
CSF |
Cerebral spinal fluid |
CSPα |
Cysteine-string protein-α |
DAT |
Dopamine transporter |
DLB |
Dementia with Lewy bodies |
DMT1 |
Divalent metal transporter 1 |
ECD |
Evolutionarily conserved domain |
ER |
Endoplasmic reticulum |
FAK |
Focal adhesion kinase |
Fe-S |
Iron-sulfur cluster |
FIP200 |
FAK family kinase-interacting protein of 200 kDa |
FPN1 |
Ferroportin |
Ft |
Ferritin |
FtH1 |
Ferritin heavy chain |
FtL |
Ferritin light chain |
FTLD |
Frontotemporal lobar dementia |
FtMt |
Mitochondrial ferritin |
GA |
Ginkgolic acid |
GABA |
γ-Aminobutyric acid |
GABARAP |
γ-Aminobutyric acid receptor-associated protein |
GABARAPL1 |
γ-Aminobutyric acid receptor-associated protein-like 1 |
GABARAPL2 |
γ-Aminobutyric acid receptor-associated protein-like 2 |
GABRR3 |
γ-Aminobutyric acid receptor subunit rho-3 |
HD |
Huntington’s disease |
HERC2 |
E3 ubiquitin protein ligase 2 |
HOPS |
Homotypic fusion and vacuole protein sorting |
HP1 |
Hydrophobic pocket 1 |
HRB |
HIV-1 Rev-binding-protein |
Hsc70 |
Heat shock cognate 70 kDa |
Hsp |
Heat shock protein |
Htt |
Huntingtin |
IRE |
Iron-responsive element |
IRP1 |
Iron regulatory protein 1 |
IMM |
Inner-mitochondrial membrane |
KO |
Knockout |
LAMP2a |
Lysosomal-associated membrane protein 2a |
LB |
Lewy body |
LC3 |
Microtubule-associated proteins 1A/1B light chain 3 |
LIP |
Labile iron pool |
LIR |
LC3 interacting region |
LN |
Lewy neurites |
MPTP |
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine |
MRI |
Magnetic resonance imaging |
MSA |
Multiple system atrophy |
mTOR |
Mammalian target of rapamycin |
mTORC1 |
mTOR complex 1 |
Munc-13 |
Mammalian uncoordinated 13 |
Munc-18 |
Mammalian uncoordinated 18 |
MVB |
Multi-vesicular body |
MWW |
Weighted-average molecular weight |
NAC |
Non-amyloid component |
NBIA5 |
Neurodegeneration with brain iron accumulation 5 |
NCOA4 |
Nuclear co-activator 4 |
NLRP3 |
NOD-like receptor protein 3 |
NOD |
Nucleotide binding domain |
Nrf2 |
Nuclear factor erythroid 2–related factor 2 |
6-OHDA |
6-Hydroxydopamine |
PAWR |
PRKC-apoptosis-WT1-regulator |
PCBP2 |
Poly-r(C)-binding protein 2 |
PD |
Parkinson’s disease |
PE |
Phosphatidylethanolamine |
PI3KC3 |
Phosphatidylinositol 3-kinase catalytic subunit type 3 |
PI3P |
Phosphatidylinositol 3-phosphate |
PNN |
Pedunculopontine nucleus |
Rab1a |
RAS-related protein in brain 1a |
Rab7 |
RAS-related protein Rab-7a |
RB1CC1 |
RB1-inducible coiled-coil protein 1 |
RPE |
Retinal pigmented epithelial cells |
SENP |
Sentrin-specific protease |
SGT |
Small glutamate-rich tetratricopeptide repeat-containing protein |
SMV |
Small single membrane vesicles |
SNAP25 |
Synaptosomal-associated protein of 25 kDa |
SNARE |
Soluble N-ethylmaleimide sensitive attachment factor receptor |
SNpc |
Substantia nigra pars compacta |
SNpr |
Substantia nigra pars reticulata |
SQSTM1 |
Sequestosome-1 (p62) |
STEAP1 |
Six transmembrane epithelial antigen of the prostate-1 |
STX17 |
Syntaxin-17 |
SUMO1 |
Small-ubiquitin-like modifier 1 |
SYNGAP |
Synaptic Ras-like GTPase-activating protein 1 |
TBC1D5 |
TBC1 domain family member 5 |
TFEB |
Transcription factor EB |
TFR1 |
Transferrin receptor 1 |
TFR2 |
Transferrin receptor 2 |
TH |
Tyrosine hydroxylase |
TGN |
trans-Golgi network |
TLR4 |
Toll-like receptor 4 |
TOM20 |
Translocase of outer membrane of 20 kDa |
TOMM20 |
Mitochondrial import receptor subunit TOM20 homolog |
t-SNARE |
Target SNARE |
UBA |
Ubiquitin-associated |
ULK1 |
Unc-51 like autophagy activating kinase |
Unc-51 |
Serine/threonine-protein kinase unc-51 |
UPS |
Ubiquitin/proteasome system |
UVRAG |
UV radiation resistance-associated gene protein |
VAMP2 |
Vesicle-associated membrane protein 2 (also known as synaptobrevin) |
VGCC |
Voltage-gated calcium channel |
VMAT2 |
Vesicular-monoamine transporter |
VPS26 |
Vacuolar protein sorting-associated protein 26A |
VPS29 |
Vacuolar protein sorting-associated protein 29 |
VPS35 |
VPS35 endosomal protein-sorting factor-like |
v-SNARE |
Vesicular SNARE |
WASH |
Wiskott–Aldrich syndrome protein and SCAR homologue |
WIPI2 |
WD repeat domain phosphoinositide-interacting protein 2 |