Table 3.
Risk factors associated with severe illness and mortality among breakthrough cases and reinfection cases in unvaccinated patients.
| Factors | Odds Ratio (95% CI) | p-Value |
|---|---|---|
| Unvaccinated | 1.55 (CI = 0.91–2.67) | 0.061 |
| Age (>median of the study) | 3.31 (CI = 1.82–4.59) | <0.001 |
| Male gender | 1.04 (CI = 0.60–1.28) | 0.694 |
| Comorbidities (>3) | 1.57 (CI = 1.46–3.81) | <0.001 |
| Obesity | 1.13 (CI = 0.85–1.47) | 0.724 |
| Smoking | 2.33 (CI = 1.16–4.52) | 0.026 |
| Ground glass opacities (>60%) | 4.09 (CI = 2.10–7.55) | <0.001 |
| Oxygen saturation (<92%) | 2.66 (CI = 1.42–3.90) | 0.004 |
| Days until second infection | 1.87 (CI = 0.92–3.77) | 0.088 |
| Days in the ICU | 1.60 (CI = 0.70–2.19) | 0.195 |
| Mixed model * | 1.36 (CI = 1.02–3.83) | 0.001 |
* All risk factors combined; CI—Confidence Interval; ICU—Intensive Care Unit.