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Inhibitory effects of ligiamycins on the proliferation of human cancer cell lines.
| IC50 (μM) | SNU638 | SK-HEP-1 | A549 | HCT116 | MDA-MB-23 |
|---|---|---|---|---|---|
| Ligiamycin A (1) | >50 | >50 | 42.0 | >50 | >50 |
| Ligiamycin B (2) | 46.2 | 34.6 | 25.9 | 20.1 | 23.7 |
| Etoposide | 2.17 | 0.24 | 0.35 | 0.66 | 2.64 |
