Table 6.

Cytochromes Inhibition Profile of the Neuroprotective Phytochemicals Used for AD, PD, and MS Treatments using SwissADME webserver.

Compound Names	CYP1A2	CYP2C19	CYP2C9	CYP2D6	CYP3A4
Curcumin	No	No	Yes	No	Yes
Aromatic turmerone	No	No	No	No	No
Resveratrol	Yes	No	Yes	No	Yes
Pterostilbene	Yes	Yes	Yes	Yes	No
Sulforaphane	No	No	No	No	No
Epigallocatechin-3-gallate	No	No	No	No	No
Andrographolide	No	No	No	No	No
Paeoniflorin	No	No	No	No	No
β-caryophyllene	No	Yes	Yes	No	No
Oridonin	No	No	No	No	No
Dihydromyricetin	No	No	No	No	No
4-O-methylhonokiol	Yes	Yes	Yes	Yes	Yes
Silibinin	No	No	No	No	Yes
Hesperidin	No	No	No	No	No
Triptolide	No	No	No	No	No
Eriodictyol	No	No	No	No	Yes
Xanthoceraside	No	No	No	No	No
Piperlongumine	No	No	No	No	No
Esculentoside A	No	No	No	No	No
Quercetin	Yes	No	No	Yes	Yes
Apigenin	Yes	No	No	Yes	Yes
Capsaicin	Yes	No	No	Yes	Yes
α-asarone	Yes	Yes	No	No	No
Galangin	Yes	No	No	Yes	Yes
Biochanin A	Yes	No	No	Yes	Yes
Baicalein	Yes	No	No	Yes	Yes
Apocynin	No	No	No	No	No
α-Mangostin	No	No	Yes	No	No
Myricetin	Yes	No	No	No	Yes
Myricitrin	No	No	No	No	No
Icariin	No	No	No	No	No
Nobiletin	No	No	Yes	No	Yes
Tenuigenin	No	No	No	No	No
Tanshinone I	Yes	Yes	No	No	Yes
Salvianolic acid B	No	No	No	No	No
Licochalcone E	Yes	No	Yes	No	Yes
Licochalcone A	Yes	No	Yes	No	Yes
Isobavachalcone	Yes	No	Yes	No	Yes
Macelignan	No	Yes	Yes	Yes	No
Ginsenoside Rg1	No	No	No	No	No
Tripchlorolide	No	No	No	No	No
Triptolide	No	No	No	No	No
Naringin	No	No	No	No	No
Cannabidiol	No	Yes	Yes	Yes	Yes
Dimethyl fumarate	No	No	No	No	No
3H-1,2-dithiole-3-thione	No	No	No	No	No
Baicalin	Yes	No	No	Yes	Yes
Matrine	No	No	No	No	No
Oleanolic Acid	No	No	No	No	No
Astragaloside IV	No	No	No	No	No
Glycyrrhizin	No	No	No	No	No
18β-Glycyrrhetinic Acid	No	No	No	No	No
Carnosol	No	No	Yes	No	No
Tanshinone IIA	Yes	Yes	Yes	Yes	Yes