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. 2022 Feb 25;101(8):e28820. doi: 10.1097/MD.0000000000028820

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Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0

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Procedure for discovering significantly altered metabolites between patients with laryngeal cancer (LC) and healthy individuals. A, The VIP value versus fold change (FC) was plotted on the y- and x-axes in volcano plot, respectively. B, The adjusted P value versus FC was plotted on the y- and x-axes in volcano plot, respectively. C, Venn diagram demonstrated the differential metabolites between LC and healthy control groups based on volcano plot analysis. VIP = variable importance in projection.