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. 2022 Jan 22;14(2):262. doi: 10.3390/pharmaceutics14020262

Table 2.

The Emix, χ, and CED of different Gla (LicA)–enhancers–CP systems.

χ (kcal/mol) Emix (kcal/mol) CED (kcal/mol)
LicA-CP 20.52 12.15 -
Gla-CP 13.00 7.70 -
LicA-CP 90-CP 6.97 4.13 2.57 × 109
LicA-IPM-CP 6.56 3.89 2.38 × 109
LicA-NMP-CP 10.87 6.44 2.21 × 109
LicA-PG-CP 19.48 11.54 2.15 × 109
LicA-POCC-CP −7.15 −4.23 2.40 × 109
LicA-SP-CP −1.77 −1.05 2.34 × 109
LicA-TP-CP 9.35 5.54 2.40 × 109
Gla-CP 90-CP 2.45 1.45 2.60 × 109
Gla-IPM-CP 3.01 1.78 2.64 × 109
Gla-NMP-CP 6.50 3.85 2.33 × 109
Gla-PG-CP 8.85 5.24 2.36 × 109
Gla-POCC-CP 2.57 1.52 2.68 × 109
Gla-SP-CP 6.37 3.77 2.38 × 109
Gla-TP-CP 6.34 3.76 2.43 × 109