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. 2022 Jan 22;14(2):262. doi: 10.3390/pharmaceutics14020262

Table 3.

The enhancement efficacy parameters of enhancers in the drug release and skin penetration process.

ERrelease ERpermeation ERcom βR/P ERsolution retention ERhydrogel retention FP/Q
LicA-CP 90 0.89 2.72 1.18 0.33 2.70 1.13 0.015
LicA-IPM 1.05 2.91 0.00 0.36 3.30 0.68 0.00
LicA-NMP 1.21 1.08 0.00 1.12 0.54 0.76 0.00
LicA-PG 1.25 0.55 1.10 2.28 1.23 1.82 0.0099
LicA-POCC 0.89 3.09 1.46 0.29 3.28 0.65 0.018
LicA-SP 1.02 2.77 1.12 0.37 3.78 0.99 0.012
LicA-TP 1.00 1.50 1.92 0.67 1.44 1.23 0.022
Gla-CP 90 1.07 2.93 1.40 0.36 2.11 1.39 0.022
Gla-IPM 1.08 1.15 0.86 0.94 1.49 1.51 0.014
Gla-NMP 1.14 2.20 0.78 0.52 1.47 1.28 0.012
Gla-PG 1.11 0.68 1.28 1.63 1.31 1.11 0.020
Gla-POCC 1.06 2.16 2.05 0.49 1.28 1.79 0.033
Gla-SP 1.14 1.15 1.14 0.99 1.04 1.90 0.017
Gla-TP 1.15 1.38 0.72 0.83 1.51 1.14 0.011