mAbs	monoclonal antibodies
MAGE	melanoma associated antigen
mCRC	metastatic colorectal cancer
MDSCc	myeloid-derivated suppressor cells
MEK	acronym for MAPK/ERK Kinase-extracellular signal-regulated kinase/extracellular signal-regulated kinase
MHC I	major histocompatibility complex I
MLH1	human mutL homolog 1
MLH6	human mutL homolog 6
MMR	mismatch repair
MSH2	MutS Homolog 2
MSI	microsatellite instability
MSI-H	microsatellite instability-high
MSI-L	microsatellite instability-low
MSS	microsatellite stable
NCRs	negative checkpoint regulators
NGS	next generation sequencing
NK	natural killer
NRAS	neuroblastoma RAS viral oncogene homolog
NTRK	Neurotrophic tyrosine receptor kinase
ORR	overall response rate
OS	overall survival
PD-1	programmed cell death-1
PD-L	programmed cell death-ligand 1
PFS	progression free survival
PI3K-AKT-mTOR	Phosphoinositide 3-kinases-Protein kinase B-mechanistic target of rapamycin
PLGF2	placental growth factor 2
POLD1 DNA	polymerase delta
POLE DNA	polymerase epsilon
RAS	rat sarcoma 2 viral oncogene homolog
RP2D	recommended phase 2 dose
RR	response rate
STATs	signal transducer and activator of transcription proteins
TAA	tumor associated antigens
TCGA	Tumor Cancer Genome Atlas
TCR	T-cell receptor
TIL	tumor infiltrating lymphocytes
TMB	tumor mutational burden
TMB-H	tumor mutational burden-high
TME	tumor microenvironment
TNFRSF	tumor necrosis factor receptor superfamily
TNFα	tumor necrosis factor-α
TNM	tumor node metastasis
TSAs	tumor specific antigens
VEGF	vascular endothelial growth factor
VISTA V	domain Ig suppressor of T cell activation
WHO	world health organization