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Expression of Ig heavy chain (HC) gene transcripts during IVPC differentiation.
| IGH Transcript | FC * | D0 ** | D10 |
|---|---|---|---|
| IGHA1 | 7.3 | 3.8 × 103 | 6.7 × 105 |
| IGHA2 | 7.1 | 7.9 × 102 | 1.2 × 105 |
| IGHD | −2.5 | 3.3 × 104 | 1.0 × 104 |
| IGHG1 | 7.4 | 2.0 × 104 | 3.3 × 106 |
| IGHG2 | 7.6 | 2.1 × 103 | 4.1 × 105 |
| IGHG3 | 6.4 | 6.5 × 103 | 5.6 × 105 |
| IGHG4 | 8.7 | 3.9 × 102 | 1.3 × 105 |
| IGHM | 2.9 | 1.3 × 105 | 9.7 × 105 |
* FC based on D10 IVPCs vs. D0 resting B cells. ** Expression levels based on normalized pseudo-counts (n = 3).
