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. 2022 Feb 25;101(8):e28823. doi: 10.1097/MD.0000000000028823

Figure 3.

Figure 3

Hazard ratios (HRs) for the comparative effectiveness of dual therapy (after meta-analysis). (A) Outcomes: HbA1c levels <7%: metformin + DPP4I (T) vs metformin + SU (C). (B) Outcomes: HbA1c levels <7%: metformin + DPP4I (T) vs SU + DPP4I (C). (C) Outcomes: HbA1c levels <7%: metformin + SU (T) vs SU + DPP4I (C). A hazard ratio greater than 1 implies target drug is associated with a higher hazard of reaching HbA1c < 7% compared with comparator drug. CI = confidence interval, DPP4I = dipeptidyl peptidase-4 inhibitors, HbA1c = glycated hemoglobin, JNUH = Jeonbuk National University Hospital, KNUH = Kangwon National University Hospital, PNUH = Pusan National University Hospital, SU = sulfonylurea.