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Physicochemical parameters of the siRNA-loaded NBs.
| Formulation | Average Diameter ± SD (nm) | Polydispersity Index (PDI) ± SD | Zeta Potential ± SD (mV) | Osmolarity (mOsm) |
|---|---|---|---|---|
| NBs | 102.3 ± 2.3 | 0.221 ± 0.02 | 27.5 ± 2.5 | 280 |
| Fluorescent NBs | 98.4 ± 5.0 | 0.220 ± 0.03 | 26.8 ± 2.2 | 282 |
| siNrf2-NBs | 97.5 ± 4.6 | 0.218 ± 0.02 | 26.2 ± 1.8 | 280 |
| siRNAneg-NBs | 100.2 ± 3.1 | 0.222 ± 0.01 | 26.4 ± 2.1 | 278 |
